Donor dendritic cells after liver and heart allotransplantation under short-term immunosuppression

Donor dendritic cells after liver and heart allotransplantation under short-term immunosuppression.

Experimental short-term immunosuppression after bowel transplantation and donor-specific bone marrow infusion.

HYPOTHESIS We previously showed in a large animal pig model that unmodified donor-specific bone marrow infusion (DSBMI) did not facilitate total bowel engraftment; in contrast, it increased the risks of rejection, infection, and graft-vs-host disease (GVHD) posttransplant. We hypothesize that continuous immunosuppression, in combination with DSBMI, might contribute to-or even trigger-these unwa...

Short and Long Term Complications after Pediatric Liver Transplantation: A Review and Literature

Background: Pediatric liver transplant is a complex surgical procedure. Pediatric liver transplantation has evolved over the last two decades into an effective and widely accepted therapy for infants and children. The aim of our report is to review the current state of knowledge and explore the incidence of complications, the involved pathogens among liver recipients to determine the effective ...

Reversal of long-term sepsis-induced immunosuppression by dendritic cells.

Severe sepsis leads to long-term systemic and local immunosuppression, which is the cause of a number of complications, including pulmonary infection. A therapeutic strategy that reverses this immunosuppression is required, given the ongoing high mortality rate of patients who have survived a severe sepsis. The present study demonstrates that experimental severe sepsis renders the lung suscepti...

Immunosuppression after Liver Transplantation